Abstract
Objectives: Lung function assessment is key in CF care, but traditional outcome measures (OMs) such as FEV1 may not be sensitive enough in the CFTR modulator era. LCI2.5 from the multiple breath washout (MBW) is a sensitive measure of small airway disease but can be lengthy in advanced lung disease. Emerging OMs include impulse oscillometry (IOS) & electrical impedance tomography (EIT). Here we report results of cross-sectional analysis of relationships between IOS, EIT, MBW & spirometry in adults with CF.
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