Abstract

The wound healing activity of topically app lied extract of bark of Ziziphus jujuba was evaluated in albino rat by excision wound model for a period of 24 days. In this study, the rats were divided into four groups, each groups continued healing process with 5 and 10% w/w methanolic extract of Zizip hus jujuba mg/cm 2 . Test duration was 24 days, wound diameter measurement using digital image analysis on days 0, 8 th , 16 th , 21 st and 24 th with biopsy of two rats from each group were taken . The results revealed that treatment with low - dose group of met hanolic extract of Ziziphus jujuba (5%) less shrinkage of wound area and also from the perspective of Histopathological change. In the second and third week, tissue had better organization than most other groups (p<0.0 1 ), but the group treated with high do ses of methanolic extract of Ziziphus jujuba (10%) had most wound

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