Abstract
Bacillus anthracis is an evolutionarily young species that presents an extremely low genetic diversity due to its slow mode of propagation, determined by short replication phases and long sporulation periods. In our ongoing efforts to elucidate phylogenetic relationships between European B. anthracis isolates, the genomes of five strains from Switzerland belonging to lineages B.Br.CNEVA and A.Br.Aust94 were sequenced. Comparative analysis with additional, available genomes from both lineages, were used to reconstruct the substructure of these populations. Genome-wide single-nucleotide polymorphism analysis revealed two phylogeographical different groups among the Swiss B.Br.CNEVA strains (central and eastern Switzerland), that define the oldest most recent common ancestor of the B.Br.CNEVA lineage currently known. Age-old practices of livestock selection, breeding and preservation of unique traits of local breeds in Alpine valleys have likely favored differentiation of regional B. anthracis populations over centuries and the emergence of genetically distinct strains in an otherwise similar environment.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
