Abstract
ABSTRACTWe report here the genome sequences and morphological characterizations of phages p000v and p000y, which infect the bacterial pathogen Shiga-toxigenic Escherichia coli O157:H7 and which are potential candidates for phage therapy against such pathogens.
Highlights
We report here the genome sequences and morphological characterizations of phages p000v and p000y, which infect the bacterial pathogen Shigatoxigenic Escherichia coli O157:H7 and which are potential candidates for phage therapy against such pathogens
Phage p000v has a genome size of 167.9 kbp, with 37.6% GC content, and phage p000y has a genome size of 169.9 kbp and 37.7% GC content
Whole-genome comparison of p000v, p000y, and E. coli phage T4 reveals that p000v and p000y are T4-like due to their high average nucleotide identity (ANI) shared with T4
Summary
We report here the genome sequences and morphological characterizations of phages p000v and p000y, which infect the bacterial pathogen Shigatoxigenic Escherichia coli O157:H7 and which are potential candidates for phage therapy against such pathogens. Both phages share 96.7% identity, obtained via a whole-genome blastn 2.2.31 [10] analysis with an e value Howard-Varona et al FIG 1 Morphological and genetic characterization of phages p000v and p000y.
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