Abstract
We have synthesized a new tumor imaging agent, 111In‐labeled porphyrin (111In‐ATN‐2). In order to image transplantable pancreatic carcinoma in Syrian golden hamsters, we investigated the biodistribution of 111In‐ATN‐2 72 hr after injecting the agent by means of whole‐body autoradiography. The efficacy of the agent was compared with that of 67Ga citrate. The images with 111In‐ATN‐2 were found to be clearer than those with 67Ga citrate. Tumor‐to‐tissue radiodistribution ratios of the former were higher than those of the latter. Thus, 111In‐ATN‐2 seems to be more useful for tumor diagnosis.
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