Abstract
In people with viral respiratory tract infections, the presence of a concomitant bacterial infection has been associated with poor clinical outcomes. For example, in patients with influenza, superimposed bacterial infection is present in 20–30% of patients [1,2] and has been associated with increased rates of shock, mechanical ventilation and mortality [1,2]. Similarly, in children with severe respiratory syncytial virus infection, multiple studies have demonstrated rates of superimposed bacterial pneumonia in excess of 30%, and this has been associated with a longer duration of mechanical ventilation [3].
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