Abstract
No abstract available.
Highlights
The right time to start antiretroviral therapy (ART) in adults and children is currently a topic of much discussion
Draft guidelines have been published by the World Health Organisation (WHO).; The WHO recommends offering ART to HIV-infected infants with virologically proven infection and WHO paediatric stage III disease (AIDS) or WHO paediatric stage I and II HIV disease and a CD4% < 200/0
In children over 18 months of age with WHO stage I or 11 HIV disease, ART is recommended if the CD4 percentage is
Summary
Tammy Meyers, FCPaed (SA) Paediatric HIV Cliuic, Chris Halli Baragwallath Hospital. Johannesburg. Metabolic complications (lactic acidosis, lipodystrophy) of ART have been well documented in adults and are being described in children." Importantly, in settings where resources are limited, delayed initiation of treatment could be a mechanism for reducing the cost of management. Adult guidelines from both Europe and North America advocate that therapy be initiated when the CD4 count is 200 - 350 cells/~1. ART has always been recommended for use in almost all children, regardless of the clinical staging of the disease. For children >18 months who are HIV antibody-positive, the WHO recommends ART if they have
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