Abstract

Sexual and reproductive function is affected by all aspects of cancer, including cancer’s biologic processes of growth and metastasis, the effects of undergoing cancer treatment, and the psychological issues that occur as a result of having cancer and receiving treatment for it. These aspects can result in changes in body appearance, infertility and sterility, and the inability to have intercourse. The changes may be made worse by additional alterations in body image, fears of abandonment, loss of self-esteem, changes in sexual identify, and concerns about self (Krebs, 2005). Human sexuality includes three separate but intertwined aspects: body image, reproductive ability, and sexuality or sexual functioning. Body image, or the way individuals see themselves or think others see them, may be altered by changes in body appearance resulting from weight loss or gain, alopecia, mucositis, fatigue, or a variety of other changes that may not be visible to others. Changes in self-esteem may occur as a result of body image alterations, resulting in decreased desire and decreased sexual activity. Reproductive function, or the ability to bear or father children, may become impossible as a result of therapyrelated infertility, and sexual functioning may be altered by changes in self-perception, decreased desire, general side effects of treatment (including cancer therapies and methods to manage side effects of therapy), or numerous other reasons. Some individuals are at higher risk for sexual side effects than others based on age, gender, type of cancer, type of cancer treatment, or concomitant medical or psychological illness (Krebs, 2001, 2005). See Figure 1 for a list of factors that contribute to sexual diffi culties.

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