Abstract
It is well known that there is an increased risk of infections in SLE patients on immunosuppression. These infections may mimic lupus flares with similar manifestations such as fever, oral ulcers, leukopenia/pancytopenia, renal involvement, pneumonitis, lymphadenopathy and others. The management of SLE in these two situations becomes contrasting. Viral infections are an important cause of morbidity and mortality in SLE patients but are often not suspected or investigated for. Herein, we present a case of SLE on immunosuppression who had recurrent herpes simplex infection, mimicking flares of the disease. The case highlights that one should have a high index of suspicion along with appropriate laboratory back up to diagnose these infections.
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