Werner’s Syndrome and Human Aging

Abstract

Historical Perspective.- On Cataract in Conjunction with Scleroderma.- Werner's Syndrome (Progeria of the Adult) and Rothmund's Syndrome: Two Types of Closely Related Heredofamilial Atrophic Dermatoses with Juvenile Cataracts and Endocrine Features a Critical Study with Five New Cases.- Werner's Syndrome: A Review of its Symptomatology, Natural History, Pathologic Features, Genetics and Relationship to the Natural Aging Process.- Werner Syndrome: A Review of Recent Research with an Analysis of Connective Tissue Metabolism, Growth Control of Cultured Cells, and Chromosomal Aberrations.- Clinical, Pathological and Genetic Aspects of the Werner Syndrome and Normal Human Aging.- Genetics and Aging: Werner's Syndrome as a Segmental Progeroid Syndrome.- Clinical, Endocrine and Metabolic Aspects of the Werner Syndrome Compared with Those of Normal Aging.- Pathology of the Werner Syndrome.- Neuropathology of the Werner Syndrome.- Werner's Syndrome and Aging: A Reappraisal.- A Comparison of Adult and Childhood Progerias: Werner Syndrome and Hutchinson-Gilford Progeria Syndrome.- Clinical, Demographic and Genetic Aspects of the Werner Syndrome in Japan.- Immunological Aspects of the Werner's Syndrome: An Analysis of 17 Patients.- Clinical and Metabolic Studies on the Werner's Syndrome: With Special Reference to Disorders of Lipid and Liver Function.- Growth Control of Werner Syndrome Cells In Vitro.- Growth Characteristics of Werner Syndrome Cells in Vitro.- Studies of SV40-Infected Werner Syndrome Fibroblasts.- Experimental Studies on Werner's Syndrome Fibroblasts.- Cell Fusion Studies in the Werner Syndrome.- Cell Fusion Studies and Biochemical Analysis of DNA Synthesis in Werner and Non-Werner Cultured Cells.- Molecular Mechanisms of Cellular Senescence: DNA Metabolism and Chromatin Change.- Histone H1 in G1 Arrested, Senescent and Werner Syndrome Fibroblasts.- Genome Reorganization During Aging of Dividing Cells.- Cellular Mechanisms of Ageing in the Werner Syndrome.- Autoradiographic Studies of DNA Replication in Werner's Syndrome Cells.- Abnormal Fibroblast Aging and DNA Replication in the Werner Syndrome.- Extrachromosomal Circular DNA and Aging Cells.- Molecular Mechanisms of Cellular Senescence: Errors in Protein Synthesis.- Protein Synthetic Fidelity in Aging Human Fibroblasts.- Analysis of Cellular Senescence through Detection and Assessment of RNAs and Proteins Important to Gene Expression: Transfer RNAs and Autoimmune Antigens.- Cytogenetics of the Werner Syndrome.- Cytogenetic Aspects of Werner Syndrome.- A Population and Cytogenetic Study of the Werner Syndrome in Sardinia.- Connective Tissue Metabolism and Disturbances in the Werner Syndrome.- Proteoglycans in the Werner Syndrome and Aging: A Review and Perspective.- Cell Surface Changes in Senescent and Werner's Syndrome Fibroblasts: Their Role in Cell Proliferation.- Acidic Glycosaminoglycans in Werner's Syndrome: Studies on Levels in Tissue, Organ, Cell and Fluid.- Acidic Glycosaminoglycans of SV40-Transformed Werner's Syndrome Cells.- Glycosaminoglycan Synthesis in Untransformed and Transformed Werner Syndrome Fibroblasts: A Preliminary Report.- Gene Action, Development and Aging: New Directions for Research in the Werner Syndrome.- The Notion of Primordial Building Blocks in Construction of Genes and Transcriptional and Processing Errors due to Random Occurrence of Oligonucleotide Signal Sequences.- Appearance of Albumin-Producing Cells in the Liver of Anabulminemic Rats on Aging and Administration of Mutagens.