Abstract
Hymenoptera venoms are rich in several kinds of allergens such as antigen-5 protein, phospholipase, hyaluronidase and protease that can elicit both large local and systemic allergic reactions. The most common symptoms after stung by insects are that the sting site become redness, swelling and painful. In severe cases, potentially life-threatening anaphylactic shock and multiorgan dysfunction syndrome(MODS) may occur after multi-attacks by insects. Hymenoptera sting is one of the three main causes of immediate type anaphylactic reaction, the other two major causes being drugs and foods. Presently, venom immunotherapy prove to be the most effective in the hymenoptera venoms allergy. Wasps are one of the largest groups within the order Hymenoptera. So studies on the wasp venom allergens can provide a good model for the diagnosis and treatment of anaphylaxis caused by wasp and other Hymenoptera. The purpose of this review is to provide up to date information on the wasp venom allergens and mechanism of wasp venom allergy.
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