Abstract

Diabetic foot ulcers (DFU) are a serious side effect of diabetes that frequently results in amputations, extended hospital stays, and infections. Peripheral artery disease (PAD), neuropathy, smoking, long-term diabetes, foot abnormalities, and a history of ulcers or amputations all raise the chance of developing DFUs. Usually, a combination of Gram-positive and Gram-negative bacteria, anaerobes, and fungi cause the infections in DFUs. Comprehensive care, such as blood glucose management, lifestyle modifications, routine foot assessments, appropriate footwear, and patient education, is the focus of prevention initiatives. For people who are at risk of DFUs, wearing shoes that fit properly, abstinence of smoking, and managing blood pressure and cholesterol are important preventive measures. the use of multiple treatments is needed for patients who already have foot ulcers. This includes debridement, pressure unloading, wound dressings, and maybe surgery. To remove necrotic tissue and to promote healing, debridement techniques include surgery, enzymatic, autolytic, and biological debridement (such as maggot therapy) are crucial. For the treatment of neuropathic ulcers, pressure modulation using methods such as total contact casts (TCC) is potential. Numerous cutting-edge wound dressings, such as hydrogels, hydrocolloids, and dressings infused with silver, help control wound moisture, enhance autolysis, and fight against infection. Revascularization, nonvascular foot surgery for abnormalities, or amputation in extreme circumstances are all possible surgical therapeutic options. strategies are required for long-term prevention and care for treating both the ulcer and the underlying causes of DFU. Ultimately, lowering the incidence of DFU and enhancing patient outcomes require a mix of efficient communication, patient education, and coordinated treatment among healthcare providers

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