Abstract
P>0.05).All 5 GERD bleeders required endoscopy treatment had multiple esophageal ulcers(LA class C or D).The majority of the GERD bleeders 63/84 had multiple esophageal ulcers. Other risk factors for patients with bleeding GERD were identified. Barrett's esophagus was found in 11/58 (19%) of GERD bleeders (26/84 had LA class D were unable to diagnose Barrett's) comparing to 10% in general GERD patients, odd ratio was 1.9 (P<0.05). NSAID use found in 13/84 (15%), odd ratio was 2.5 (P<0.05). 18/84 of the GERD bleeders were taking maintenance treatment for GERD at the time of the bleeding. Only 6/84 GERD bleeder had abdominal pain or reflux symptomes on admission. CONCLUSIONS:AUGIB is a serious complication of GERD.It required admission to hospital, blood transfusion and endoscopic treatment.Barrett's esophagus,NSAID use, and multiple esophageal ulcers were significant risk factors for GERD bleeding.REFERENCES:(1)PJKahrilas, NEnglJMed 2008;359:1700-7. (2)Boonpongmanee et al Gastrointestinal Endosc 2004;59:788-94
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