Abstract
Dear Editor, We would like to share ideas on “Vulvar Aphthous Ulcer Following Pfizer-BioNTech COVID-19 Vaccine - A Case Report.1.Drucker A Corrao K Gandy M: Vulvar aphthous ulcer following Pfizer-BioNTech COVID-19 vaccine - a case report.J Pediatr Adolesc Gynecol. 2021 Oct 27; (S1083-3188(21)00325-9Online ahead of print)https://doi.org/10.1016/j.jpag.2021.10.007Abstract Full Text Full Text PDF PubMed Scopus (4) Google Scholar Drucker et al concluded the following: “Summary and conclusion- Vaccination, in general, has been associated with….caused by a similar mechanism and should be considered a rare side effect of this vaccine.”1.Drucker A Corrao K Gandy M: Vulvar aphthous ulcer following Pfizer-BioNTech COVID-19 vaccine - a case report.J Pediatr Adolesc Gynecol. 2021 Oct 27; (S1083-3188(21)00325-9Online ahead of print)https://doi.org/10.1016/j.jpag.2021.10.007Abstract Full Text Full Text PDF PubMed Scopus (4) Google Scholar A mucocutaneous effect of COVID-19 vaccination is possible. The pathogenesis is still inconclusive. For post-CPVOD-19 vaccination vulvar aphthous ulcer, further investigation and monitoring of clinical symptoms is necessary. The genital ulcer might be the first presentation of Behcet's disease, which is a rare problem observed following COVID-19 vaccination.2.Tagini F Carrel L Fallet B et al.Behcet's-like adverse event or inaugural Behcet's disease after SARS-CoV-2 mRNA-1273 vaccination?.Rheumatology (Oxford). 2021 Oct 7; (Online ahead of print): keab751https://doi.org/10.1093/rheumatology/keab751Crossref PubMed Scopus (3) Google Scholar For a possible pathogenesis, COVID-19 vaccination can induce a hyperviscosity problem,3.Joob B Wiwanitkit V: Expected viscosity after COVID-19 vaccination, hyperviscosity and previous COVID-19.Clin Appl Thromb Hemost. Jan-Dec 2021; 27 (10760296211020833)Crossref PubMed Scopus (49) Google Scholar which is a rare but possible clinical problem associated with Behcet's disease.4.Ricart JM Vaya A Todolí J et al.Haemorheological alterations in Behcet's disease are not related to a tendency for venous thrombosis.Thromb Res. 2005; 115: 399-404Abstract Full Text Full Text PDF PubMed Scopus (12) Google Scholar None
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