Abstract
The QT interval of the electrocardiogram (ECG) represents myocardial depolarization and repolarization. Prolongation of the QT interval corrected for heart rate (QTc interval) may result in life-threatening arrhythmias, such as polymorphous ventricular tachycardia (VT) of the torsades de pointes (TdP) type and ventricular fibrillation. 1 Long QT syndrome, sympathetic activation, sleep, marked bradycardia, a long list of certain drugs, hypocalcemia, hypokalemia, hypomagnesemia, myocarditis, diffuse myocardial disease, cerebrovascular injury, autonomic neuropathy, arsenic, organophosphates, severe malnutrition and HIV may prolong the QT interval. QTc interval is calculated using Bazett’s formula and should not exceed 440 ms except in infants. 1
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