Abstract
A 72-year-old woman underwent screening via esophagogastroduodenoscopy (EGD). A dose of vonoprazan 10 mg was administered once a day for symptoms that may be due to mild reflux esophagitis, for about a month. EGD revealed diffuse gastric mucosal redness throughout the gastric body (Figure A). Magnifying endoscopy with narrow-band imaging showed an oval crypt opening and diffuse redness of the surrounding mucosa (Figure B). Serum Helicobacter pylori antibody tests were negative. A biopsy specimen revealed hemorrhage with congestion beneath the basement membrane of the superficial foveolar epithelium and oxyntic gland dilatation with marked parietal cell protrusions (Figure C).
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