Vitamin D deficiency as a risk factor for arterial hypertension and chronic kidney disease in obese patients

Abstract

Background and Aims : To establish a relationship between serum vitamin D levels and risk factors for cardiovascular disease in obese patients of working age.Methods: The study included 100 people aged 44.8±6.4 years, BMI 33.1±3.2kg/m2 without disorders of carbohydrate metabolism, atherosclerosis, arterial hypertension, kidney damage.The level of vitamin D, leptin, resistin, HOMA index, GFRwere investigated. The examination of visceral adipose tissue: the epi- and pericardial fat depots; VAT1 - measurement at the level of the navel from the inner surface of the rectus abdominis to the posterior wall of the aorta and L4; the thickness of the posterior perirenal VAT on the right and left and the area of perirenal fat on both sides.Conclusions: In obese patients, a low level of vitamin D is associated with an increase in markers of metabolic distress, increase BP and a decrease in renal function. Background and Aims : To establish a relationship between serum vitamin D levels and risk factors for cardiovascular disease in obese patients of working age. Methods: The study included 100 people aged 44.8±6.4 years, BMI 33.1±3.2kg/m2 without disorders of carbohydrate metabolism, atherosclerosis, arterial hypertension, kidney damage.The level of vitamin D, leptin, resistin, HOMA index, GFRwere investigated. The examination of visceral adipose tissue: the epi- and pericardial fat depots; VAT1 - measurement at the level of the navel from the inner surface of the rectus abdominis to the posterior wall of the aorta and L4; the thickness of the posterior perirenal VAT on the right and left and the area of perirenal fat on both sides. Conclusions: In obese patients, a low level of vitamin D is associated with an increase in markers of metabolic distress, increase BP and a decrease in renal function.