Abstract
Here, we demonstrate the visual evoked blood flow change in trilaminar retinal vasculature in rodents using OCT capillary velocimetry. A custom-built spectral-domain optical coherence tomography operates on 800 nm region performed all the imaging. In-vivo measurements were conducted on dark-adapted Brown Norway rats. The retinal blood flow velocity was calculated using a modified dynamic light scattering (DLS) – OCT method. As a result, the blood flow velocity in arterioles, venules, and capillaries in the retinal vasculature can be resolved. Flicker stimulation triggered heterogeneous responses – reduced flow velocity in large vessels vs. increased flow velocity in capillaries.
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