Abstract
mBackground: Rigid gas permeable (RGP) and silicone hydrogel (SH) contact lenses with specific designs are currently being used to improve visual function in patients with keratoconus. However, there are minimal data available comparing the effects of these lenses on visual function in patients with keratoconus. The objectives of this study were to compare visual acuity and contrast sensitivity using spectacles, RGP lenses, and SH lenses, and to evaluate the effects of RGP and SH lenses on higher-order aberrations and visual quality in eyes with keratoconus. The relationship between visual outcomes, aberration, and visual quality were also examined. Methods: This was a pilot study involving 13 eyes from nine subjects with keratoconus. Subjects were fitted with RGP and SH contact lenses. Visual acuity and contrast sensitivity were measured using Snellen and Pelli-Robson charts, respectively. Ocular aberrations and visual quality were measured using an OPD-Scan II device. All measurements were conducted before and after contact lens wear. Results: Significantly better visual acuity was obtained with RGP lenses than with spectacles or SH lenses (P,0.001). No significant difference in contrast sensitivity values was detected between RGP and SH lenses (P=0.06). Both SH and RGP lenses significantly reduced total ocular and higher-order aberrations (P,0.001) when compared with spectacles, but RGP lenses reduced trefoil, coma, and spherical aberrations more than SH lenses. No significant difference in astigmatic aberrations was found between RGP and SH lenses (P=0.12). Negative correlations were found between visual acuity and coma aberration and contrast sensitivity with higherorder aberrations and coma, trefoil, and astigmatic aberrations. Regarding visual quality, no significant difference was found between RGP and SH lenses, but RGP significantly improved visual quality when compared with spectacles (P=0.04). Conclusion: RGP lenses provided better visual acuity and greater reduction of aberrations than spectacles or SH lenses in patients with keratoconus. However, more data are needed to
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