Abstract
Viruses, the vehicle for cancer gene therapy: A Review
Highlights
In accordance with genetic alteration, oncogene relates to any gene that converts normal cells into cancer cells lead to an abnormal proliferation of cells
There are more than 100 recognized oncogenes, most of which have been recognized in human tumors
It has been indicated that the transportation of genetic products to tumor cells or normal cells to eradicate or decrease tumor mass is the main component in cancer gene therapy
Summary
Cancer is said to be among the leading causes of mortality and morbidity with about 14 million new and 8.2 million cancer-related fatalities in 2012. In accordance with genetic alteration, oncogene relates to any gene that converts normal cells into cancer cells lead to an abnormal proliferation of cells. These proteins generally prevent apoptosis induced by DNA replication and cell division (Engel et al, 2014; and Romli et al, 2017) This implies that if these genes are mutated, their proteins lose its functions and cause uncontrolled proliferation of cells, leading to cancer growth. Cancer cells may have distinct origins, so this differs considerably in cell genetics, transcriptions, translations and cell profiles (Blanpain, 2013; and Ghaemi et al, 2017) This implies that it is crucial to design the therapeutic methods based on the biology of tumor cells. All this shows the desperate need for therapeutic methods to progress
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
