Abstract
A prospective study of 29 children treated with vigabatrin (VGB) as add on therapy for epilepsy included ophthalmic examination before and at 6-month intervals for 6.5 years, at Sultan Qaboos University Hospital, Sultanate of Oman.
Highlights
A prospective study of 29 children treated with vigabatrin (VGB) as add on therapy for epilepsy included ophthalmic examination before and at 6-month intervals for 6.5 years, at Sultan Qaboos University Hospital, Sultanate of Oman
Hancock E et al, from the UK, in reviewing the literature on the effectiveness of vigabatrin compared to ACTH and predisone, concluded that the optimum therapy for West syndrome remains uncertain
Regular eye examination including perimetry is recommended in patients treated with vigabatrin
Summary
A prospective study of 29 children treated with vigabatrin (VGB) as add on therapy for epilepsy included ophthalmic examination before and at 6-month intervals for 6.5 years, at Sultan Qaboos University Hospital, Sultanate of Oman. Low-dose synthetic ACTH therapy for West syndrome is effective and is associated with less toxicity than higher dose regimens. Ito and his colleagues have previously reported on the effectiveness of low-dose ACTH regimens for infantile spasms
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