Vesicular Darier's disease (so-called benign familial pemphigus); a variant of Darier's disease.

Abstract

PELS AND GOODMAN¹in 1939 reported the case of a patient with Darier's disease in whom vesicle formation was a prominent feature. They stated that "this report of a case of Darier's disease was prompted by the unusual moisture and vesiculation, which were prominent features, and particularly by the confusion of the diagnosis with possible pemphigus vegetans." One month later Hailey and Hailey²published an article under the title of "Familial Benign Chronic Pemphigus" in which 4 patients who had an apparently similar syndrome were described. Goodman³in a letter in 1939 wrote: The data presented by Drs. Hailey lead inescapably to the conclusion that they were dealing with Darier's disease of the rare vesicular and bullous type described by Dr. Pels and me in the aforementioned article. All the features which they described for their cases should maintain this diagnosis: namely, chronicity, familial occurrence, benignancy,