Abstract
Abstract 1.1. The influence of protein (in the form of gelatin) on the acidity and pepsin of the gastric juice of patients suffering from peptic ulcer was investigated by means of a modified double histamine test. 2.2. The hydrogen-ion concentration, the free acid, and the pepsin were reduced. The total titrable acidity was not appreciably influenced. 3.3. On the basis of in vitro experiments the reduction of the hydrogen-ion concentration and free acidity of the gastric juice may be ascribed to the acid-combining power of the protein. 4.4. The reduction of the pepsin content of the stomach, on the basis of in vitro experiments, cannot be ascribed to the protein per se, but possibly to a reduced secretion of pepsin or a retarded conversion of pepsinogen to pepsin.
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