Abstract
The aerial parts of selected Potentilla species (P. anserina, P. argentea, P. erecta, P. fruticosa, P. grandiflora, P. nepalensis, P. norvegica, P. pensylvanica, P. crantzii and P. thuringiaca) were investigated in order to determine their contents of polyphenolic compounds. The results showed that P. fruticosa has relatively high concentrations of tannins (167.3 ± 2.0 mg/g dw), proanthocyanidins (4.6 ± 0.2 mg/g dw) and phenolic acids (16.4 ± 0.8 mg/g dw), as well as flavonoids (7.0 ± 1.1 mg/g dw), calculated as quercetin. Furthermore, we investigated the in vitro inhibitory effects of aqueous extracts from these species against cariogenic Streptococcus spp. strains. It was found that the tested samples moderately inhibit the growth of oral streptococci. However, all the preparations exhibited inhibitory effects on water-insoluble α-(1→3)-, α-(1→6)-linked glucan (mutan) and artificial dental plaque formation. The extract from P. fruticosa showed the highest anti-biofilm activities, with minimum mutan and biofilm inhibition concentrations of 6.25–25 and 50–100 µg/mL, respectively. The results indicate that the studied Potentilla species could be a potential plant material for extracting biologically active compounds, and could become a useful supplement for pharmaceutical products as a new anticariogenic agent in a wide range of oral care products.
Highlights
Potentilla species (Rosaceae) and their extracts have been highly valued in many different ethnic cultures for hundreds of years throughout the world
The purpose of our study was to evaluate the effects of aqueous extracts from the aerial parts of selected Potentilla species against cariogenic Streptococcus spp. strains
Our results show that P. fructicosa is rich in polyphenolic compounds, and they are consistent with earlier studies on reported by Shikov et al [19] and Miliauskas et al [20]
Summary
Potentilla species (Rosaceae) and their extracts have been highly valued in many different ethnic cultures for hundreds of years throughout the world. The genus Potentilla is well known for the difficulties it presents in terms of identifying species, as well as the frequency of synonyms which occur. A common phenomenon within this genus is interspecies hybridization and apomixis. This has resulted in a great morphological variability of species [1,2,3,4,5,6,7]. The application of modern phytochemical methods have led to the isolation of a wide range of natural compounds from the various species. Most of the biological activities of Potentilla extracts can be explained by their high contents of polyphenolics
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