Variable Selection Methods in High-dimensional Regression—A Simulation Study

Abstract

A challenging problem in the analysis of high-dimensional data is variable selection. In this study, we describe a bootstrap based technique for selecting predictors in partial least-squares regression (PLSR) and principle component regression (PCR) in high-dimensional data. Using a bootstrap-based technique for significance tests of the regression coefficients, a subset of the original variables can be selected to be included in the regression, thus obtaining a more parsimonious model with smaller prediction errors. We compare the bootstrap approach with several variable selection approaches (jack-knife and sparse formulation-based methods) on PCR and PLSR in simulation and real data.