Abstract
BackgroundThis prospective study is to evaluate the potential value of sonographic measurements in the flaccid penis for the screening of arteriogenic impotence.MethodsA consecutive series of 260 Chinese males consulting for sexual dysfunction and 54 controls underwent sonographic examination. The sonographic parameters were correlated with the clinical gold standards, including the international index of erectile function (IIEF) and penile erectile hardness grading scale (EHGS). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and area under the receiver operating characteristic curve (AUROC) of flaccid peak systolic velocity (PSV) in predicting patients with normal function were analyzed.ResultsThe mean cavernous PSV of both sides in the patients with sexual dysfunction ranged from 7.76 to 11.12 cm/sec with a stepwise increase in IIEF and EHGS grading scale (P < .05). The cutoff value of flaccid PSV for the differential diagnosis of grade 4 of IIEF-5 or EHGS was 8.20–8.90 cm/sec, with an AUROC of 0.657–0.724, specificity of 82.96–86.84% and PPV of 95.20–96.60%, respectively.ConclusionsThis simple flaccid PSV measurement is a specific tool for screening arteriogenic impotence.
Highlights
This prospective study is to evaluate the potential value of sonographic measurements in the flaccid penis for the screening of arteriogenic impotence
The mean peak systolic velocity (PSV) of both sides in the patients consulting for sexual dysfunction ranged from 7.76 to 11.12 cm/sec with a stepwise increase in index of erectile function (IIEF) and erectile hardness grading scale (EHGS) grading (P < .05) (Table 1, Fig. 1).the differences between grade 4 of IIEF-5 or EHGS and other grades were significant (Fig. 1)
Diameter and resistance index (RI) in both sides of the cavernous artery showed no significant difference among different grades of IIEF-5 or EHGS, with a mean value of 0.48– 0.58 mm for diameter and a median value of 1.00 for RI
Summary
This prospective study is to evaluate the potential value of sonographic measurements in the flaccid penis for the screening of arteriogenic impotence. Erectile dysfunction (ED) is a common worldwide and potentially treatable problem with an incidence of 50% in the general male population aged between 40 and 70 years [1]. In addition to psychological and metabolic factors and relational problems, arteriogenic causes play important roles in erectile dysfunction [2,3,4]. The peak systolic velocity (PSV) of the cavernous artery measured after the Doppler investigation in the flaccid state would avoid these disadvantages. It has been reported that PSV values that were measured in the flaccid state show a significant correlation with post-ICI PSV and might be
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