Abstract
Objective To evaluate the value of fetal intelligent navigation echocardiography with color flow imaging (5D Heart Color) in the display of key diagnostic elements in basic fetal echocardiographic views. Methods The heart volumes datasets of 220 fetuses were collected and the offline analysis was conducted. Pearson correlations was used to compare the detection rate of blood flow element between 5D Heart Color software and color Doppler flow imaging(CDFI) in basic fetal echocardiographic views, and the detection rate of blood flow between normal fetuses (control group) and fetuses with cardiovascular abnormalities(case group). Bland-Altman analysis was used to prove consistency and reliability of the results. Results Totally 384 fetal heart volume datasets were collected from 220 fetuses, and 317 volume datasets of 200 cases could be used for the analysis, with the acquiring success rate of 82.6%. 5D Heart Color software and CDFI showed a close correlation in displaying key cardiovascular blood flow information in key fetal echocardiographic diagnosis sections (r=0.88, P<0.05); The detection rates of blood flow elements in control group and case group were 91.9% and 87.3%, respectively, with an average of 89.6% (r=0.9, P<0.05). Bland-Altman analysis showed close consistency between inter- and intra-observations in the detection rates of blood flow elements, and their 95% confidence intervals were (-0.1/+ 0.09) and (-0.09/+ 0.1), respectively, and the points outside the 95% confidence interval were 5.4%(17/231) and 5.7%(18/231), respectively. Conclusions 5D Heart Color software shows similar usefulness in the displaying key blood flow elements, comparing with CDFI, demonstrating higher reliability and repeatability in displaying fetal echocardiographic diagnosis views and diagnostic blood flow elements. Key words: Echocardiography; Congenital heart disease; Fetus; Fetal intelligent navigation echocardiography
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