Abstract

The purpose of this study is to validate Eclipse's electron Monte Carlo algorithm (eMC) in heterogeneous phantoms using radiochromic films and EGSnrc as a reference Monte Carlo algorithm. Four heterogeneous phantoms are used in this study. Radiochromic films are inserted in these phantoms, including in heterogeneous media, and the measured relative dose distributions are compared to eMC calculations. Phantoms A, B, and C contain 1D heterogeneities, built with layers of lung‐ (phantom A) and bone‐ (phantoms B and C) equivalent materials sandwiched in Plastic Water. Phantom D is a thorax‐anthropomorphic phantom with 2D lung heterogeneities. Electron beams of 6, 9, 12 and 18 MeV from a Varian Clinac 2100 are delivered to these phantoms with a 10×10 cm2 applicator. Monte Carlo simulations with an independent algorithm (EGSnrc) are also used as a reference tool for two purposes: (1) as a second validation of the eMC dose calculations, and (2) to calculate the stopping power ratio between radiochromic films and bone medium, when dose is measured inside the heterogeneity. Percent depth dose (PDD) film measurements and eMC calculations agree within 2% or 3 mm for phantom A, and within 3% or 3 mm for phantoms B and C for almost all beam energies. One exception is observed with phantom B and the 6 MeV, where measured PDDs and those calculated with eMC differ by up to 4 mm. Gamma analysis of the measured and calculated 2D dose distributions in phantom D agree with criteria of 3%, 3 mm for 9, 12, and 18 MeV beams, and criteria of 5%, 3 mm for the 6 MeV beam. Dose calculations in heterogeneous media with eMC agree within 3% or 3 mm with radiochromic film measurements. Six (6) MeV beams are not modeled as accurately as other beam energies. The eMC algorithm is suitable for clinical dose calculations involving lung and bone.PACS numbers: 87.10.Rt, 87.55.km

Highlights

  • A small number of studies have already been published on the validity of this commercially available algorithm

  • macro Monte Carlo algorithm (MMC) is marketed under the trade name electron Monte Carlo, and is available on the Eclipse treatment planning system (Varian Medical Systems, Palo Alto, CA). Another vendor has released a voxel-based Monte Carlo calculation platform (Oncentra MasterPlan, Nucletron Inc., Veenendaal, The Netherlands) for electron beams derived from VMC++.(4,5) The goal of this study is to evaluate the accuracy of the electron Monte Carlo algorithm (eMC) algorithm in heterogenous media

  • This paper presents the results of a validation study of eMC dose calculations involving heterogeneities using radiochromic film dosimetry (GAFCHROMIC EBT, International Specialty Products, Inc., Wayne, NJ)

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Summary

Introduction

A small number of studies have already been published on the validity of this commercially available algorithm. The emphasis is generally on the verification of output factors and dose distributions in water.[6,7] Monte Carlo simulations are especially advantageous in conditions of medium heterogeneity and irregular surfaces where full electron transport simulation is necessary to accurately calculate dose distributions. To the best of our knowledge, there are no validation studies incorporating dose measurements in a clinical electron beam (i.e., inside the heterogeneities themselves – they were done in presence of heterogeneities), nor of situations combining irregular surfaces and heterogeneities. Such irradiation conditions, can occur everyday in a radiation oncology clinic

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