Abstract

BackgroundNowadays, irrational use of antimicrobials has threatened public health. It’s necessary to expand the use of clinical practice guideline (CPG) on antimicrobial for facilitating the proper use of antimicrobial. However, the utilization status of CPG on antimicrobial and the influencing factors, especially the ones at the organizational level, remain largely unknown.MethodsA cross-sectional questionnaire survey was conducted on a sample among physicians from 16 public hospitals in the eastern, central and western parts of China. A multilevel regression model was employed to examine factors associated with physicians’ utilization of CPG on antimicrobial.ResultsA total of 815 physicians were included in this study. About 80% of the surveyed physicians reported their adherence to the CPG on antimicrobial. Dimensions of “subjective norm”, “perceived risk” and “behavioral intention” from the domain of physician belief, a dimension of “ease of use” from the domain of CPG traits, and dimensions of “top management support” and “organization & implementation” from the domain of hospital practice were significantly associated with physicians’ utilization of CPG on antimicrobial. And except for working department, most demographics characteristics of the physician were not found to be significantly related to the CPG use. In addition, it also showed that region is a significant factor affecting physicians’ CPG use.ConclusionsThis study depicted the current status of CPG on antimicrobial and comprehensively identified its potential determinants not only from the three domains at the individual level, such as physician belief, but also from the location region at the organizational level. The results will provide a direct reference for the implementation of CPG on antimicrobial.

Highlights

  • IntroductionIrrational use of antimicrobials has threatened public health

  • Nowadays, irrational use of antimicrobials has threatened public health

  • Since there was a dearth of literature on the utilization of clinical practice guideline (CPG) on antimicrobial and its potential determinants, this study described the current status of CPG utilization and comprehensively identified its potential influencing factors from the domains of physician belief, CPG traits, and hospital practice

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Summary

Introduction

Irrational use of antimicrobials has threatened public health. It’s necessary to expand the use of clinical practice guideline (CPG) on antimicrobial for facilitating the proper use of antimicrobial. The rise in the prevalence of irrational use of antimicrobial has weakened its original effectiveness and. To address AMR, various measures have been taken by health authorities in China [4]. Among these measures, Clinical practice guideline (CPG) is a professional recommendation for physicians basing on current best. Deng and Liu BMC Health Services Research (2020) 20:282 evidence, and it has been commonly reported for its significant role in standardizing clinical treatment and improving the outcomes of medical services [5]. This guideline did not serve as a mandatory requirement for physicians and health institutions, and there was no regulation or policy on the compulsory implementation of CPG

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