Abstract
Uterine leiomyosarcoma (LMS) is rare malignant neoplasm. Approximately 2% to 5% of all uterine malignancies [1]. Uterine leiomyosarcoma usually occur with vaginal bleeding, in the less frequently seen pelvic pain, pelvic mass, and uterine enlargement. Surgery is the primary treatment for uterine leiomyosarcoma. A 56 year old woman presented at vaginal bleeding. On admission, CT scan revealed lung and breast metastatic nodules. First she underwent surgery and then received chemotherapy. After 2 years than surgery she underwent total mastectomy. Histopathology report showed metastasis of leiomyosarcoma. In this report we describe an unusual case of uterine leiomyosarcoma with metastases to the breast.
Highlights
Leiomyosarcoma is rare and aggressive soft tissue sarcoma most often seen uterine, gastrointestinal or soft tissue origin
Four case of uterine leiomyosarcoma with breast metastasis was reported in the literature to our knowledge
We report another case of uterine leiomyosarcoma with breast metastasis
Summary
Leiomyosarcoma is rare and aggressive soft tissue sarcoma most often seen uterine, gastrointestinal or soft tissue origin. Women are most affected and ıt occur in the 5th 6th decades of life. Distant metastasis case of leiomyosarcoma is rare. Most seen places are the lung, kidney and liver. Therewithal thyroid, brain, bone, skeletal muscle, heart, parathyroid gland, oral cavity and breast metastasis have been reported. Classical treatment of leiomyosarcoma is total hysterectomy and bilateral salphingo-ooferectomy, and for some cases hormonotherapy, chemotherapy and radiotherapy. Four case of uterine leiomyosarcoma with breast metastasis was reported in the literature to our knowledge. We report another case of uterine leiomyosarcoma with breast metastasis
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