Uso de complejos híbridos estabilizados de ácido hialurónico en melasma. Serie de casos

Abstract

Melasma is a hypermelanosis characterized by hyperpigmented brown spots that appear in photoexposed areas. Its multifactorial etiology involves genetic and hormonal factors, exposure to ultraviolet radiation, and vascular alterations. It occurs mainly in women, and its evolution is chronic. The diagnosis is clinical, and the treatment is generally combined, as no universal treatment exists. Hybrid hyaluronic acid complexes are formed by two hyaluronic acid chains (one high-molecular weight chain and another low-molecular one). They are currently used for aesthetic purposes, but their use in clinical dermatoses has already been documented. The objective of this article is to show the results of two Mexican patients with melasma who were administered intradermal stabilized hybrid complexes of hyaluronic acid with a protocol of two applications separated by four weeks between the first and second application. With the publication of this series of cases, we contribute to demonstrating the safety and effectiveness of using stabilized hyaluronic acid hybrid complexes for dermatoses with pigmentation disorders such as melasma.