Abstract

Introduction: Researchers have not yet determined a method for individually dosing tDCS. This lack of dosing and titration has likely contributed to the reproducibility and clinical trial difficulties. Using single-pulse transcranial electrical stimulation (TES) thresholds as a surrogate for tDCS, we aimed to determine whether objective recordings (TMS neurophysiology, individual MRI measures and scalp resistance) might determine individual tDCS dosing.

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