Abstract

RECENT REPORTS 1 indicate that the administration of measles vaccine for active immunization of susceptible children has not yet reached desirable levels, and that 20 million children under the age of 10, living in the United States, are unprotected. Several factors probably account for this, including lack of information, cost of the procedure, and the possibility or fear of reaction. The latter has been specifically related to egg-allergic children, of whom there are conservatively estimated to be over 50,000 among the allergic pediatric population of the United States. Since reactions to virus vaccines have occurred in the past among eggallergic children, 2-4 the manufacturers of virus vaccines have routinely cautioned that such children should not receive live, attenuated virus vaccine immunizations. In a previous study, 5 we administered live, attenuated measles virus vaccine to 11 children from 1 to 6 1/2 years of age, each of whom repeatedly demonstrated severe

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