Abstract

SummaryAn artificial kidney of the Skegg-Leonards type was used successfully to lower blood barbiturate levels in dogs. Approximately 15 to 25% of the intravenously injected pentobarbital, 35% of intravenously injected amobarbital, and 40 to 70% of intra-peritoneally injected phenobarbital were recovered in the respective dialysates. This therapy was life saving in the phenobarbital experiments, of some value in the amobarbital intoxication, but of questionable value in pentobarbital poisoning.

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