Abstract
From April, 2000 to January, 2005, 46 consecutive patients with chronic osteomyelitis of the lower extremity underwent surgical debridement and reconstruction with anterolateral thigh perforator flaps (8 cases were combined with vastus lateralis muscle flaps). All wounds were open for a minimum period of 6 weeks (average of 17 months; range from 6 weeks to 59 months). The average patient age was 44 years (ranged from 18 to 71 years), there were 35 males and 11 females, and the average follow up period was 21.5 months (ranged from 3 to 53 months). The cause of injury was an open fracture in 10 cases, secondary wound complications after reduction in 21 cases, and diabetic foot in 15 cases. Surface defects ranged from 50 to 201 cm2. Wounds were debrided an average of 2.5 times, then reconstructed with flaps and treated with antibiotics for 6 weeks. Antibiotic beads were used in 6 cases and secondary bone graft procedures were performed in 14 cases 3 months after flap coverage.
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