Abstract

The aim of the study was to describe clinical characteristics and bladder assessment in children with Non-Monosymptomatic Nocturnal Enuresis (NMNE) in coastal region of Croatia. Records on 85 patients with NMNE were retrospectively reviewed. Bladder assessments were performed in all children. In this research we: (i) compare clinical characteristics and features of bladder assessment: uroflowmetry, post void residuals (PVR) and bladder wall thickness between boys and girls with NMNE and we compare (ii) clinical characteristics and bladder assessment between children with primary and secondary NMNE. There were 46 girls and 39 boys. The total of 59 children had primary NMNE and 26 children had secondary NMNE. Uroflow pattern was abnormal in 42% of all children with NMNE. Abnormal uroflow pattern in children with NMNE was more often in girls than in boys (P < 0.05) and in children with secondary than in children with primary NMNE (P < 0.05). Ultrasound evidence of bladder wall thickness was more frequent in boys than in girls. Girls were more likely to have dysfunctional voiding and larger residual urinary volume than boys. Abnormal uroflow pattern in children with NMNE was more often in girls than boys and in children with secondary than in children with primary NMNE.

Highlights

  • The International Children’s Continence Society (ICCS) defines enuresis as wetting in discrete portions while asleep in a child older than five [1]

  • Primary nocturnal enuresis (PNE) is defined as nocturnal wetting in a child who has never been dry on consecutive nights for longer than 6 months

  • Nocturnal polyuria was calculated from frequency volume chart and defined as nocturnal production of the urine > 130% of expected bladder capacity according to the age

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Summary

Introduction

The International Children’s Continence Society (ICCS) defines enuresis (or nocturnal enuresis, NE) as wetting in discrete portions while asleep in a child older than five [1]. Enuresis which occur without lower urinary tract symptoms or a history of bladder dysfunction is monosymptomatic. Enuresis with lower urinary tract symptoms such as change in voiding frequency, daytime wetting, dribbling, and holding manoeuvres is non-monosymptomatic (or polysymptomatic). Among those children with frequent NE (2 or more wet nights per week), 68.5% were classified as monosymptomatic and 31.5% as non-monosymptomatic [7]. The other etiological factors are an arousal disturbance during sleep and lack of inhibition of the micturition reflex. Urodynamic studies are not required [10, 11]

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