Abstract

Studies in ambulatory, fed diabetic patients and normal subjects, with continuous in vivo blood glucose analysis for 48-hour periods, have permitted an examination of the relationship between simultaneous levels of blood and urinary glucose. There is a significant correlation between the blood glucose level and the urinary glucose level measured quantitatively for the period of observation. Semiquantitative determination of urinary glucose with the use of colorimetric test paper (Tes-Tape) on second-voided preprandial urine specimens is at best a rough indication of the prevailing blood glucose level and in some instances may be misleading. Semiquantitative glucose analysis of first-voided and second-voided urine specimens, bracketing a urine collection period, provides a clinically useful estimate of the urinary glucose level during the collection period.

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