Abstract
Chronic urticaria (CU) defined as hives lasting more than 6 weeks1 is a challenging disease to treat due to its unpredictable nature, the lack of prognostic predictors, and minimal data on predictors of treatment response. CU affects between 0.5% and 5% of the population with the estimated incidence rate of 1.4% per year.1 Quality of life of patients with CU is significantly poor2 with associated angioedema (in approximately 40% of cases3) perceived as a particularly alarming symptom. Hives commonly last 3-5 years with 85% of patients reporting resolution of urticaria within 5 years.
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