Abstract
Small microorganisms are colonised in various sites of human body including urinary tract. Although they could not be determined by standard culture techniques, up-to-date it has been suspected that urinary system is not out of any microorganisms. Simply, total of these microorganisms form urinary microbiome. Contribution to well being of tract or cause of diseases and which microorganisms play the role are questions to be answered. Bladder cancer recurrence, prostate cancer ethiology, relationship with renal Stones, chronic pelvic pain, bladder pain, urinary incontinence are most studied subjects about urinary microbiome to detect targeted therapies, explore protective therapeutic strategies or find new biomarkers.
Highlights
Human body includes 10 times more microbial cells than human cells and most of them can’t be specified by standard culture technics
They could not be determined by standard culture techniques, up-to-date it has been suspected that urinary system is not out of any microorganisms
16S rRNA is the most specific part of bacterial genom, which is used in protein synthesis [4]
Summary
Human body includes 10 times more microbial cells than human cells and most of them can’t be specified by standard culture technics. These microbial cells are encoded in the human genome, having great impact on various diseases or well-being of different organ systems. Microbiota is the total of microorganisms in special organs, which genome forms microbiome. Most of the studies maintain that the development of the microbiome starts at birth. Human microbiome Project (HMP) was started by National Institute of Health in 2008 to determine all the microbial genome sequences and to define its role in someones health and disease. The HMP is extracting 16S rRNA and making metagenomic sequencing to determine microbiome. 16S rRNA is the most specific part of bacterial genom, which is used in protein synthesis [4]
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