Abstract
Background: Pregnancy induced hypertension is the most common complication of pregnancy. It affects 5-7% of pregnant women. Pregnancy induced hypertension is characterized by vasospasm which is associated with platelet aggregation and reduced uteroplacental flow. In addition to these, altered renal function tests can also worsens the condition. This influences the maternal as well as fetal outcome. Aims: To prevent the complications of pregnancy induced hypertension and for proper management of these cases present study was conducted. Materials and Methods: The present study was conducted in 300 subjects grouped into 120 cases of normal pregnancy, 150 cases of pregnancy induced hypertensives, 30 cases of eclamptics and serum uric acid level was measured in these. Results and Discussion: elevated level of serum uric acid was seen with increase in gestation period and rise in diastolic blood pressure. The p- value was estimated by student t-test in different groups and was found to be< 0> Conclusion: Hence Serum Uric acid is the significant and reliable indicator for pregnancy induced hypertension to prevent the fetal and maternal mortality and morbidity. Keywords: Eclampsia, Gestational hypertension, Hyperuricemia, Pre-eclampsia, Pregnancy induced hypertension(PIH).
Highlights
Hypertensive disorders are the commonest medical disorders during pregnancy which contributes to maternal and perinatal mortality and morbidity
Gestational hypertension is defined as a sustained rise of blood pressure to 140/90 mm Hg or more on at least two occasions 4 or more hours apart beyond 20th week of pregnancy or within first 48hrs of delivery in previously normotensive women whereas pre-eclampsia can be defined as multisystem disorder of unknown etiology characterized by development during pregnancy and serum uric acid level correspond to the severity of pre- eclampsia
In the present study total number of 300 cases were studied. These included the normal pregnancy of 120 cases which were divided into first, second and third trimester of 40 cases each and 150 cases of pregnancy induced hypertension. 150 cases of pregnancy induced hypertension were subdivided into 50 cases of mild PIH, moderate PIH, severe PIH each and included 30 cases of eclamptic cases with history of convulsions and high blood pressure
Summary
Hypertensive disorders are the commonest medical disorders during pregnancy which contributes to maternal and perinatal mortality and morbidity. Women with pregnancy induced hypertension are found with increased level of uric acid in maternal blood due to decreased renal urate excretion. In addition to these, altered renal function tests can worsens the condition This influences the maternal as well as fetal outcome. Aims: To prevent the complications of pregnancy induced hypertension and for proper management of these cases present study was conducted. Materials and Methods: The present study was conducted in 300 subjects grouped into 120 cases of normal pregnancy, 150 cases of pregnancy induced hypertensives, 30 cases of eclamptics and serum uric acid level was measured in these. Conclusion: Serum Uric acid is the significant and reliable indicator for pregnancy induced hypertension to prevent the fetal and maternal mortality and morbidity
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