Abstract

Unilateral thickening was observed in the lower wall of fetal arteries on the placental surface adjacent to the intervillous space. The unilateral muscular growth seemed to have its onset at 12 weeks' gestation increasing in frequency with increments of gestational age, mid later being associated with intimal thickening in the term placenta. Out of 202 consec utive term placentas, 170 (84.1 per cent) showed this peculiar thickening of the lower arterial wall by single cross section. In contrast to arteriosclerosis, the medial muscular growth was more pronounced than the intimal thickening, and there was no remarkable lipid deposition. The etiology of such unilateral lesion is discussed in relation to the pathogenesis of art eriosclerosis.

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