Unicentric Castleman's disease: An unusual cause of neck swelling

Abstract

Introduction: Castleman’s disease is a rare disorder in which there is a benign proliferation of lymphoid tissue. There are two clinical entities namely, unicentric Castleman’s disease with the disease confined to a single anatomic lymph node and a multicentric Castleman’s disease characterized by generalized lymphadenopathy, constitutional symptoms, a more aggressive clinical course and relatively poorer prognosis. The most common histopathological subtype is the hyaline vascular variant. Case Report: We present the case of an 18-year-old female presented with a painless right-sided neck swelling which was completely excised and diagnosed to have hyaline vascular variant of unicentric Castleman’s disease. This disorder carries an excellent prognosis and does not