Abstract

Introduction. Undifferentiated pleomorphic sarcoma, previously known as malignant fibrous histiocytoma, is the most common soft tissue sarcoma in adults, and retroperitoneum is the second most common location. Case Report. We present a case of a 60-year-old female patient with a painless mass in the left hemiabdomen. Computed tomography revealed a well defined retroperitoneal mass, while magnetic resonance showed a lobulated hypointense mass on T1-weighted and heterogeneous on T2-weighted images 180 x 230 x 250 mm in size, with intense peripheral enhancement. The patient underwent complete tumor excision, as well as reoperation after local recurrence. After histopathological and immunohistochemical analysis of the operating material, the diagnosis of malignant fibrous histiocytoma (giant cell type) was made. Conclusion. Radiological imaging has a limited diagnostic accuracy in undifferentiated pleomorphic sarcomas and definitive diagnosis relies on histopathological confirmation.

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