Abstract
9651 Background: Early phase (EP) trials are typically offered to ACP once they exhaust standard treatment options. Limited knowledge exists about what patients understand regarding EP trials as they approach the end of standard treatments. Methods: ACP were recruited from five clinics at an academic medical center with an EP trials program. Patients were eligible if treating oncologists deemed them likely to exhaust standard treatment in 6-12 months. Eligible patients completed a 60 minute qualitative interview. Clinical research was only discussed if patients raised it during the interview. Interviews were audio recorded and transcribed; Atlas.ti was used for thematic coding. Results: 82 patients were recruited; 60 mentioned clinical research. Thematic analysis showed that understanding of clinical research differed along two dimensions: Accuracy and Specificity. Some ACP accurately described research; others had inaccurate understandings. Patients described the research process with different degrees o...
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