Abstract

Understanding and combating age-related muscle weakness: MYOAGE challenge

Highlights

  • Ageing is a hot topic due to the changing demography of developed countries that have seen life expectancy reach an all-time high

  • Combating muscle weakness requires an integrated multi-disciplinary approach that gathers expertise from gerontologists, epidemiologists, cellular and molecular biologists and physiologists. This special issue of Biogerontology features original articles and review papers from the MYOAGE study centred on the topic of skeletal muscle ageing

  • We explore the causes and consequence of reduced muscle mass leading to sarcopenia, muscle weakness and mobility limitations, in order to decipher some potential targets on which to act to allow a ‘‘better ageing’’ for the elderly population

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Summary

Introduction

Ageing is a hot topic due to the changing demography of developed countries that have seen life expectancy reach an all-time high. Understanding and combating age-related muscle weakness: MYOAGE challenge Universite Pierre et Marie Curie, Paris 6, UM76, Institut de Myologie, 47, bd de l’Hopital, Paris 75013, France e-mail: gillian.butler-browne@upmc.fr

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