Abstract
In Umbria region 67,5% of women (aged 25-64) are screened regularly, meaning every 3 years. Considering regional tariffs and vaccine acquisition cost, the vaccination of 12-year-old girls with a 90% coverage could prevent 13 cases of cervicocarcinoma and 6 related deaths and thus results to be cost-effective (23.398 €/QALY). When the vaccination programme is extended to 16-year-old girls a further 13 cancer cases and 5 deaths could be prevented, with a very similar cost-effectiveness ratio. In Umbria region, the net cost for woman vaccinated is 155 € for the single cohort and 159 € for the multiple cohort.
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