Abstract

 
 
 Ultrastructural studies were carried out on liver obtained after the appear- ance of clinical signs of bunostomosis from a group of experimentally infested lambs.
 In the hepatocytes of the liver severe changes affecting the endoplasmic reticulum, especially the rough one, and the nucleic chromatin were determined.
 The formation of lipid drops into the injured hepatocytes followed the way of a fat degeneration rather than of a lipid infiltration. Both the liver parenchyma and mesenchyma compounds were affected.
 This is an evidence of a direct toxic pathogenic action of the etiology agent. These data add to the knowledge of the bunostomosis pathogenesis more information about the leading role of the toxic factor.
 
 
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