Abstract
Circadian rhythm, an internal 24-hour cycle biological clock, regulates important biologic functions such as metabolism, body temperature, heart and respiratory rate, circulating levels of hormones, sleep-wake pattern, behaviour. It is also a very important in regulation of the cardiovascular (CV) system components such as arterial blood pressure, pulse, endothelial function. In this comprehensive review of the literature, we will discuss how interaction between environment/behavior stressors and circadian phases modulate individual cardiovascular risk. Potential therapeutical targets will be also discussed.
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