Abstract
The effects of carbidopa and phenylthiourea on dopa decarboxylase and phenoloxidase in relation to their involvement in sclerotization were assessed after injection of these compounds to late last instar Corcyra cephalonica larvae. Carbidopa, on administration, inhibited dopa decarboxylase activity but served as a substrate of phenoloxidase, leading to the development of yellow coloured pupal cuticle. The larvae, injected with phenylthiourea, had reduced phenoloxidase activity, and a prolonged larval period. The control mechanisms of tanning in these insects have been discussed with reference to tyrosine metabolism.
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