Abstract
1. 1. It has been demonstrated that during stress-induced melanogenesis in the goldfish, Carassius auratus L, the level of tyrosinase in the skin is increased several fold and that this increase precedes pigmentation. 2. 2. The increase in tyrosinase activity is more pronounced in the particulate fraction than in the soluble fraction. 3. 3. In three varieties of the goldfish (xanthic, wild-type grey and black moor), the tyrosinase activity parallels the degree of pigmentation of the skin. This is due to a higher level of particulate tyrosinase in the pigmented fish. 4. 4. Considerable tyrosinase activity is present in skin homogenates prepared from totally xanthic fish. Therefore, in addition to the level of tyrosinase activity, other factors may regulate melanogenesis.
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